
Tesamorelin
CAS #: 218949-48-5
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Tesamorelin Overview
Tesamorelin is a synthetic analog of growth-hormone-releasing hormone (GHRH) composed of 44 amino acids with a stabilizing modification. It has been studied extensively in controlled experimental settings for its influence on the growth-hormone axis, metabolic signaling, and pathway dynamics.
History
Tesamorelin was developed as a stabilized GHRH analog to extend signaling activity. Research initially focused on its interaction with GHRH receptors and broadened into metabolic and systemic models exploring its role in growth-hormone regulation.
Tesamorelin Structure

- CAS #:
- 218949-48-5
- Molecular Formula:
- C221H366N72O67S
- Molecular Weight:
- 5135.9 g/mol
- PubChem ID:
- 16137828
Research Findings
Tesamorelin has been studied in endocrine, metabolic, and systemic models, with reports of activity in GHRH-receptor signaling, growth-hormone release, and downstream metabolic pathways within preclinical research systems.
Key Areas of Research:
- Endocrine: GHRH receptor, GH axis
- Metabolic: lipid and glucose pathway dynamics
- Secretory: growth-hormone release
- Systemic: signaling, pathway resilience
References
- Synthesis & Characterization. Solid-phase peptide synthesis, purification, and analytical confirmation of identity and purity.
- Preclinical Research. Reported activity across structural, vascular, and systemic models in controlled experimental settings.
- Stability Studies. Lyophilized stability and reconstitution behavior under controlled cold-chain storage.
- Analytical Verification. Third-party HPLC and mass-spectrometry verification of mass, identity, and purity.



